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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM3
All Species:
15.76
Human Site:
S711
Identified Species:
24.76
UniProt:
P25205
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25205
NP_002379.2
808
90981
S711
S
Y
D
P
Y
D
F
S
D
T
E
E
E
M
P
Chimpanzee
Pan troglodytes
XP_001151750
808
90957
S711
S
Y
D
P
Y
D
F
S
D
T
E
E
E
M
P
Rhesus Macaque
Macaca mulatta
XP_001106966
808
90990
S711
S
Y
D
P
Y
D
F
S
D
T
E
E
E
M
P
Dog
Lupus familis
XP_538960
916
102667
S819
S
Y
D
P
Y
D
F
S
D
T
E
E
E
M
P
Cat
Felis silvestris
Mouse
Mus musculus
P25206
812
91528
E711
P
Y
D
F
S
E
A
E
T
Q
M
P
Q
V
H
Rat
Rattus norvegicus
XP_001070728
813
91641
A711
D
P
Y
D
F
S
E
A
E
R
E
M
P
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN2
812
91233
F712
E
S
Y
D
P
Y
D
F
S
D
A
E
Q
E
M
Frog
Xenopus laevis
Q7ZXZ0
806
90528
T711
F
S
D
T
E
D
E
T
P
V
V
H
T
P
K
Zebra Danio
Brachydanio rerio
NP_997732
807
90502
T710
Y
D
P
Y
D
F
D
T
E
T
D
I
P
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511048
819
90900
P705
D
E
E
D
I
E
P
P
Q
P
D
A
G
D
L
Honey Bee
Apis mellifera
XP_625020
811
91329
D709
S
D
D
D
S
Y
I
D
E
A
A
K
R
V
T
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
F668
V
E
E
A
L
R
L
F
R
V
S
T
I
E
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
G674
E
H
D
A
G
A
T
G
G
T
V
D
G
H
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
D684
E
N
D
T
A
N
V
D
S
E
T
A
D
P
M
Baker's Yeast
Sacchar. cerevisiae
P24279
971
107499
V795
R
R
S
T
A
S
S
V
N
A
T
P
S
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
86
N.A.
92.9
93.3
N.A.
N.A.
81.4
80.1
75.9
N.A.
62.5
62.7
30.8
N.A.
Protein Similarity:
100
99.8
100
87.2
N.A.
96.6
97
N.A.
N.A.
92
90.7
88.1
N.A.
80
78.6
49.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
13.3
6.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
0
13.3
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
33.3
26.6
N.A.
N.A.
13.3
20
26.6
N.A.
20
33.3
6.6
N.A.
Percent
Protein Identity:
N.A.
47.6
N.A.
49.3
39.8
N.A.
Protein Similarity:
N.A.
66
N.A.
68.1
54.7
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
14
7
7
7
0
14
14
14
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
14
60
27
7
34
14
14
27
7
14
7
7
7
0
% D
% Glu:
20
14
14
0
7
14
14
7
20
7
34
34
27
14
0
% E
% Phe:
7
0
0
7
7
7
27
14
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
7
7
0
0
0
14
0
7
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
7
0
7
7
% H
% Ile:
0
0
0
0
7
0
7
0
0
0
0
7
7
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% K
% Leu:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
27
14
% M
% Asn:
0
7
0
0
0
7
0
0
7
0
0
0
0
0
0
% N
% Pro:
7
7
7
27
7
0
7
7
7
7
0
14
14
14
27
% P
% Gln:
0
0
0
0
0
0
0
0
7
7
0
0
14
14
0
% Q
% Arg:
7
7
0
0
0
7
0
0
7
7
0
0
7
0
0
% R
% Ser:
34
14
7
0
14
14
7
27
14
0
7
0
7
7
0
% S
% Thr:
0
0
0
20
0
0
7
14
7
40
14
7
7
0
7
% T
% Val:
7
0
0
0
0
0
7
7
0
14
14
0
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
34
14
7
27
14
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _